Friday, October 26, 2012

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Source: http://kashwealthsystem.com/health/2012/10/22/stop-smoking-self-hypnosis-audio-download-with-ebook/

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Source: http://alysia-occultist.blogspot.com/2012/10/health-and-fitness-stop-smoking-self.html

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Season over for Browns LB Scott Fujita

BEREA, Ohio (AP) ? Browns linebacker Scott Fujita will be placed on injured reserve with a neck injury, ending his stormy season.

Fujita, one four players suspended by NFL Commissioner Roger Goodell for his role in the New Orleans Saints' bounty scandal, was inactive the past two games. He last started on Oct. 7 in a game against the New York Giants. Browns coach Pat Shurmur does not know if Fujita, an 11-year veteran and one of the league's most informed players, will retire.

The 33-year-old Fujita had neck surgery in college.

Fujita had his three-game suspension reduced to one by Goodell. However, Fujita was angered by a letter he received from the commissioner and harshly criticized Goodell for his handling of the Saints' situation and questioned his track record on player safety.

Source: http://news.yahoo.com/season-over-browns-lb-scott-fujita-163457189--nfl.html

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Wednesday, October 24, 2012

Color Kinetics Unveils London Eye

Photo copyright David Morrell, courtesy Lighting Technology Projects.

Color Kinetics Inc. announced last week the unveiling of its latest international landmark installation, the British Airways London Eye. Named the "World's Leading Attraction" this year by the World Travel Awards, the London Eye is the world's tallest observation wheel at 450? high, and is the newest in a growing number of high-profile destinations to undergo a complete lighting overhaul with Color Kinetics' LED lighting technology.

"The London Eye has become a 21st century symbol for Britain, and it's a thrill to see this long-planned project come to realization. We've achieved an ambitious goal in bringing dynamic, visually appealing color to the structure while at the same time eliminating the maintenance costs and requirements of the previous fluorescent system. We're extremely pleased with the results, and believe Londoners and visitors alike will agree," said Kevin Dyer, Head of Technical Operations for the British Airways London Eye.

Situated on the South Bank of the River Thames and often called the "Gateway to London," the London Eye is visited by more than 10,000 people daily. It was previously lit by fluorescent tubes that proved costly to maintain, and required the manual installation of gels to produce colored light for special events.

Color Kinetics was approached to replace this system with an LED-based alternative. Approximately 640 ColorCast? 14 units were supplied, installed and programmed by UK-based Architainment Lighting Ltd. and Lighting Technology Projects. Each unit may be individually programmed to generate millions of colors that are seamlessly produced by Chromacore? technology, as opposed to the use of colored gels. This technology gives the London Eye the cost-effective ability to display precise colors for corporate clients and special occasions, while predominantly displaying white light

"Internationally recognized installations have become one of the benchmarks that define Color Kinetics' market success, and we're honored to put our signature on an iconic structure like the British Airways London Eye," says Bill Sims, president and CEO, Color Kinetics. "This project reflects an accelerating trend as maintenance-intensive lighting systems are displaced by LED alternatives - first in applications of color and increasingly in the use of white light. Though six years away, we can envision the Eye playing a colorful, welcoming role when London hosts the 2012 Olympic Games."

Today Color Kinetics' lighting systems are installed in many notable sites in and around London. These include Victoria Plaza, Berkeley Homes Tower at Tabard Square, Plantation Place, Great Ormond Street Hospital, City Place House, 27 Knightsbridge, and Millennium Square at Bristol Harbour.

The newly Color Kinetics-illuminated London Eye is visible from more than a mile away. Because Color Kinetics' lighting systems are compatible with the industry-standard DMX protocol, the ColorCast 14 units integrate seamlessly with two Pharos LPC2 controllers, enabling the creation of dynamic light shows on demand. The rugged, exterior-grade units incorporate Powercore? technology to directly accept line voltage, eliminating the need for external power supplies and easing installation.

Photo copyright David Morrell, courtesy Lighting Technology Projects.

Source: http://livedesignonline.com/architainment/color_kinetics_london_eye_011607/?imw=Y

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Clintons land in Haiti to showcase industrial park

CARACOL, Haiti (AP) ? Secretary of State Hillary Rodham Clinton encouraged foreigners to invest in Haiti as she and her husband Bill led a star-studded delegation gathered Monday to inaugurate a new industrial park at the center of U.S. efforts to help the country rebuild after the 2010 earthquake.

Actors Sean Penn and Bill Stiller, fashion designer Donna Karan and British business magnate Richard Branson were among the luminaries at the opening of the new Caracol Industrial Park, which is projected to create thousands of jobs more than 100 miles from the quake-ravaged capital of Port-au-Prince.

Hillary Rodham Clinton told a roomful of investors gathered for a luncheon that she had made Haiti a priority when she became Secretary of State.

"We had learned that supporting long-term prosperity in Haiti meant more than providing aid," she said. "It required investments in infrastructure and the economy that would help the Haitian people achieve their own dreams.

"So we shifted our assistance to investments to address some of the biggest challenges facing this country: creating jobs and sustainable economic growth," she added.

Earlier Monday, thousands of Haitians lined the roadway to wave at her motorcade as it wound its way from the airport. Hillary Rodham Clinton and other U.S. officials, including Labor Secretary Hilda Solis and Sen. Patrick Leahy, a Democrat from Vermont, toured a housing development for industrial park workers supported by the U.S. Agency for International Development.

The Secretary of State noted there were three presidents gathered in one room to celebrate the opening: her husband, former American President Bill Clinton, current Haitian President Michel Martelly and his predecessor Rene Preval.

Bill Clinton, now a U.N. special envoy for Haiti, arrived in Caracol separately from his wife.

The Clintons and their allies hope that the $300 million industrial facility will transform the northern part of this impoverished country by providing thousands of desperately needed jobs.

But some Haitians say the industrial park does little more than replicate failed efforts from the past and will benefit outsiders more than Haitians. They also worry it will harm some of the few pieces of undamaged environment that still exist in Haiti.

"It's really all-in on this project, and there's a high bar to deliver," said Laurent Dubois, a historian who teaches at Duke University and is author of "Haiti: The Aftershocks of History." ''It really needs to deliver in a big way so that people will think, yeah, this was the right thing to do."

The stakes are high in large part because the Clintons have been so heavily involved.

The Caracol project was in the works before the earthquake but it became a top priority for the Obama administration soon after the disaster. Hillary Rodham Clinton's chief of staff, Cheryl Mills, has made almost monthly visits to the site on Haiti's northern coast.

Bill Clinton also took an interest. He attended the project's groundbreaking a year ago with Martelly.

The $124 million put in by the U.S. makes the park Washington's biggest single investment in the aftermath of the quake and it is certain to shape the legacy of the Clintons, who last visited Haiti together in 1975 on a wedding gift following their honeymoon in Mexico.

Monday's trip is Hillary Rodham Clinton's third to Haiti since the earthquake, and there have been more than a dozen visits by her husband, who was co-chairman of an earthquake recovery panel before its mandate ended a year ago.

The industrial park to be inaugurated by the Clintons was built on a 617-acre (250-hectare) site meant to "decentralize" Haiti's economy away from the crowded capital of Port-au-Prince and help develop the long-neglected countryside.

The anchor tenant is South Korean apparel giant Sae-A Trading Co. Ltd, which begun production in May. It has agreed to create 20,000 permanent jobs within six years and also build 5,000 houses. Backers say the entire park has the potential to generate up to 65,000 jobs in all.

Sae-A, which shipped 76,000 T-shirts to Wal-Mart in the United States on Oct. 15, says it is training 1,050 people it has hired, 70 percent of them from the area surrounding Caracol. Daniel Cho, a representative of Sae-A in Haiti, said the employees will be paid almost $5 for eight hours of work.

A local paint manufacturing company, Peintures Caraibes SA, became the second tenant in July and will export paint made by Sherwin Williams along with its own paint; production begins next month. It's supposed to hire 350 people.

Details are still being worked on to bring in other tenants, but the project's architects hope its duty-free status and a 15-year tax holiday will lure more.

Everyone agrees Haiti needs jobs. The country of about 10 million people is among the world's poorest, and unemployment and underemployment hover around 60 percent.

Despite the promises of up to 65,000 jobs at the site, and projections of possibly 133,000 more jobs through related cottage industries, the Caracol project has drawn much skepticism.

Critics say it's not much different from the factories to make baseballs for the U.S. sport that were built in the 1970s and 1980s under the regime of playboy dictator Jean-Claude "Baby Doc" Duvalier.

Those jobs prompted thousands of farmers to leave their fields for the capital, and agricultural areas suffered from neglect. Shantytowns like Cite Soleil emerged to house the new workers. The factories got tax breaks but there was no income to offset Duvalier's alleged plundering of state coffers.

Haiti was supposed to become the "Taiwan of the Caribbean" but instead suffered through economic collapse brought on by political instability.

"This is: Been there, done that," Alex Dupuy, a Haiti-born sociologist who teaches at Wesleyan University in Connecticut, said of the Caracol project.

Because of the tenants' tax breaks, outside investors will have more to gain than Haitians, he said.

"This is not a strategy that is meant to provide Haiti with any measure of sustainable development ... The only reason those industries come to Haiti is because the country has the lowest wages in the region," Dupuy said.

Backers of Caracol stress that it will bring tens of thousands of jobs to an area where subsistence farming has long been the only alternative to migration. Jean Cherenfant, mayor of Cap-Haitien, a seaside city 13 miles (21 kilometers) from Caracol, sees the facility as a boon.

"We don't have a lot of employers here, and we're talking about several hundred thousand jobs," Cherenfant said by telephone. "I will not go along with those people who are pessimistic."

____

Associated Press writer Josh Lederman contributed to this report from Caracol, Haiti.

Source: http://news.yahoo.com/clintons-land-haiti-showcase-industrial-park-070901823.html

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Police release dash cam video of car-chase crash that killed Texas teen

by KHOU.com Staff

kens5.com

Posted on October 23, 2012 at 4:32 PM

HOUSTON?Police have released dash cam video of the crash that killed 16-year-old Shawn Williams over the weekend.

The video shows an officer starting the chase of the fleeing pickup truck. It had been seen at a shoplifting incident at San Jacinto Mall, and then was found minutes later at another shoplifting attempt at a nearby Academy store.

The truck shown bouncing through a ditch had just rammed a Baytown police vehicle, and then raced south on Garth road at a high rate of speed.

The officer backs off and keeps a visual on the truck as it races in oncoming traffic and blows through red lights.

Two miles later, as another officer is laying down spike strips, there is an explosion. The footage shows the car holding Williams and 17-year old Shay Hollingshead in flames. Two people are seen running, later identified as Shannon Joe Chauncey and Jennifer Jenkins, who were captured moments later.

Police believe they did all they could to avoid the loss of life. Williams? family says that is not their concern right now. Their focus is on celebrating the life of a young man loved by everyone who knew him.

"We teach our kids that ?live life like it?s your last day," said Shawn?s father. "He would do everything. And he always lived for the benefit of someone else."

"I didn?t think I would ever see people in the community this attached to one of my children, to our family, you know. Thank you," said Shawn?s mother Pleshette.

The argument over his death and who is to blame will wait for another day. In the meantime, Shay Hollingshead remains in critical condition.

Source: http://www.kens5.com/video/featured-videos/Police-release-dash-cam-video-of-car-chase-crash-that-killed-Texas-teen-175492381.html

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Bayonet company calls Obama 'ignorant' because troops still use bayonets

(Hollie McKay, Fox News) --?Designers, stylists and fashion industry publicists routinely clamor to outfit First Lady Michelle Obama, with press releases flying out the door any time she sports a certain brand. Fashion publications praise her designer selections and several books have been published that are solely devoted to analyzing her style and taste.

However, the fashion world has remained particularly quiet on the Ann Romney fashion front, with many questioning whether or not outspoken Obama supporter Anna Wintour is keeping stylists and designers away, silently threatening their standing should they endeavor to promote their outfitting of the wife of a Republican presidential hopeful.

Read more at Fox News.

Source: http://www.610wtvn.com/cc-common/news/sections/newsarticle.html?feed=104707&article=10516788

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Tuesday, October 23, 2012

Discovery of biological energy-sensing switch could have broad implications for biology and medicine

ScienceDaily (Oct. 21, 2012) ? Biochemists at The Scripps Research Institute (TSRI) have discovered a genetic sequence that can alter its host gene's activity in response to cellular energy levels. The scientists have found this particular energy-sensing switch in bacterial genes, which could make it a target for a powerful new class of antibiotics. If similar energy-sensing switches are also identified for human genes, they may be useful for treating metabolism-related disorders such as type 2 diabetes and heart disease.

"This discovery adds a new dimension to our understanding of how cells sense and manage their energy levels, which is one of the most important processes in biology," said the study's senior author, Martha J. Fedor, a professor the departments of Chemical Physiology and Molecular Biology and a member of the Skaggs Institute for Chemical Biology at TSRI.

The findings are described online ahead of print on October 21, 2012, in the journal Nature Chemical Biology.

A Fuel Sensor

This type of gene-switching sequence is known as a riboswitch because it appears on the strand of ribonucleic acid (RNA) that is first transcribed from a gene's DNA. Unlike other known riboswitches, which have relatively limited functions, this one acts as a sensor for the basic molecular fuel that powers all living cells and controls many genes.

The newly discovered riboswitch detects a small molecule known as adenosine triphosphate (ATP), the standard unit of chemical energy in all known organisms on our planet. Scientists had thought that cells use only large and relatively complex proteins to sense these all-important energy molecules and adjust cell activities accordingly. No one had found ATP sensors among riboswitches, which can alter cell activity at a more fundamental level -- usually by interrupting a gene's transcription from DNA.

Moreover, previously described riboswitches are relatively simple feedback sensors that affect narrow metabolic pathways. Most of them merely sense and adjust the expression rate of their own host gene. "This is the first riboswitch that is known to be involved in global metabolic regulation," said Fedor.

In recent years, the Fedor team had found hints that such a riboswitch could exist. Many RNA sequences with possible riboswitch activity had never been characterized, and several riboswitches in bacteria sense molecules that are closely related to ATP. Fedor and a graduate student in her laboratory, Peter Y. Watson, therefore set out to find bacterial riboswitches that could indeed sense ATP.

Caught in the Act

The task was more challenging than it might have seemed. Watson could not simply expose suspected riboswitches to ATP and see which ones stuck best to the energy molecules. ATP is present in high concentrations in cells, and its interactions with its known protein sensors are necessarily fleeting, low-affinity affairs. Interactions with a riboswitch would be expected to look the same. "Such interactions are really too weak to be detected using traditional methods," Watson said. But he found evidence that an RNA interaction with an ATP-like molecule would occur in a way that allows the brief coupling to be caught in the act -- using a burst of ultraviolet radiation, which can create a strong chemical crosslink between two molecules.

In this way, he discovered a stretch of apparent ATP-binding RNA known as the ydaO motif. Watson performed structure-mapping analyses of ydaO to confirm that it binds to ATP and to determine precisely where it binds. Attaching ydaO to a "reporter" gene, he found that in bacterial cells, the reporter gene's expression level stayed low when ATP levels were normal and rose sharply when ATP levels dropped -- as would be expected if ydaO is really an ATP-sensing riboswitch. Even in unaltered cells of a test bacterium, B. subtilis, levels of the genes that normally contain the ydaO motif rose and fell in the same way in response to changing ATP levels.

The ydaO motif occurs in the large subset of bacteria known as gram-positive bacteria. Across these bacterial species, it has been found, to date, on 580 separate genes. "These ydaO-regulated genes encode proteins that have a wide variety of functions, from cell wall metabolism to amino acid transport," Watson said. "It makes sense that a riboswitch in control of such disparate processes would be responding to a central metabolite such as ATP."

New Possibilities

The finding has basic scientific importance because it is the first known example of a riboswitch that binds ATP; it is also the first known riboswitch that has such broad regulatory functions. "It opens up the possibility that RNA switches are involved in the general regulation of metabolism," said Fedor.

The fact that ydaO motifs serve as "off-switches" for key bacterial genes also makes them a potential target for new antibiotics. "Hitting these riboswitches with a small-molecule, ATP-mimicking drug so that they can't turn on genes that promote bacterial growth and survival could be a viable approach," said Fedor.

Her laboratory will now search for other ATP-sensing riboswitches in bacteria and in higher organisms, including humans. A human ATP-sensing riboswitch, if targeted appropriately by drugs, might be able to alter cell activity in ways that help treat common metabolic disorders. Type 2 diabetes, which presently affects several hundred million people worldwide, is known to feature the improper regulation of ATP levels in cells.

Funding for the study, "The ydaO motif is an ATP-sensing riboswitch in Bacillus subtilis," was provided by the Skaggs Institute for Chemical Biology at TSRI.

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The above story is reprinted from materials provided by Scripps Research Institute.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.


Journal Reference:

  1. Peter Y Watson, Martha J Fedor. The ydaO motif is an ATP-sensing riboswitch in Bacillus subtilis. Nature Chemical Biology, 2012; DOI: 10.1038/nchembio.1095

Note: If no author is given, the source is cited instead.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/top_news/top_environment/~3/0xPUbneVCp0/121021133909.htm

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